IMMUNOLOGY
Thursday 25 February 2016
IMMUNOLOGY
III B.Sc., SEMESTER-V MAIN CORE-7: IMMUNOLOGY
Unit I
Types of immunity: Innate and acquired, Passive and active.
Types of immunity: Innate and acquired, Passive and active.
Lymphoid organs: Primary and secondary lymphoid organs-
Thymus
bone marrow
bursa fabricius
spleen
lymph node
GALT & BALT
Lymphocytes: Macrophages, T and B cells –origin
Lymphocytes: Macrophages, T and B cells –origin
Lymphocytes: Macrophages, T and B cells –origin
Lymphocytes: differentiation and functions
Role of lymphokines and cytokines in an immune response
Unit II
Antigen
Super Antigen
haptens
Immunoglobulin: structure, types & functions
Genetic basis of Antibody diversity.
Vaccines and Toxoids
Unit III
Acquired Immune Response: Primary and Secondary immune response.
Humoral immunity
Antigen recognition
cell interactions
clonal proliferation
interleukins
antibody synthesis
regulation of antibody synthesis
Cell mediated immunity: Role of cyototoxic T lymphocytes
Cell mediated immunity TD cells
Cell mediated immunity NK cells
Cell mediated immunity Macrophages
Immunity to infection: Mechanism
Antigenic drift, antigenic shift
antigen
Unit IV
HLA: structure & functions
Organ transplantation
HLA typing
Autoimmunity: Concept, mechanism
Autoimmune diseases
Graves disease
SLE
serum sickness
Rheumatoid arthritis
Hypersensitivity: Definition, mechanism & types
Tumor immunology: Tumor antigens immune surveillance
Tumor antigens immune surveillance
Tumor immunotherapy.
Unit V
Immunological techniques : Production of antisera
Aggulation
Precipitation reactions
Immunoflorescence
Immunodiffusion
Immunoelectrophoresis
RIA
ELSAFISH
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